18046-21-4|Fentiazac|2-(4-(4-chlorophenyl)-2-phenylthiazol-5-yl)acetic acid|-范德生物科技公司

Fentiazac

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names：
2-(4-(4-chlorophenyl)-2-phenylthiazol-5-yl)acetic acid
CAS号：
18046-21-4
MDL Number：
MF(分子式)： C17H12ClNO2S MW(分子量)： 329.798
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Fentiazac
英文别名	Fentiazac; BR-700; BR-700; BR-700; CH800; CH-800; CH 800; NSC 282191; WY-21,894; WY21,894; WY 21,894; WY-21894; WY21894; WY 21894; Norvedan; Donorest; Flogene
CAS号	18046-21-4
SMILES	O=C(O)CC1=C(C2=CC=C(Cl)C=C2)N=C(C3=CC=CC=C3)S1
Inchi	InChI=1S/C17H12ClNO2S/c18-13-8-6-11(7-9-13)16-14(10-15(20)21)22-17(19-16)12-4-2-1-3-5-12/h1-9H,10H2,(H,20,21)
InchiKey	JIEKMACRVQTPRC-UHFFFAOYSA-N
分子式 Formula	C17H12ClNO2S
分子量 Molecular Weight	329.798
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Fentiazac(CAS:18046-21-4 ):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Fentiazac, also known as BR-700, is a non-steroidal anti-inflammatory agent used to treat inflammation and pain.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Dowell PS, Pierce DM, Franklin RA, Norris R, Harries H, Whiteland H. The pharmacokinetics of fentiazac and its metabolite, p-hydroxyfentiazac, after twice-daily oral administration to male volunteers. Xenobiotica. 1984 Dec;14(12):947-53. PubMed PMID: 6531942.

[2]Chang J, Carlson RP, Lewis AJ. A comparative study of the antiinflammatory activity of fentiazac and its major metabolite, p-hydroxy fentiazac. Agents Actions. 1984 Oct;15(3-4):443-7. PubMed PMID: 6441470.

[3] Bunde B, Deckers Y, Dequeker J. Fentiazac in rheumatoid arthritis: comparison with sulindac and long-term tolerance. Curr Med Res Opin. 1983;8(5):310-4. PubMed PMID: 6340972.

[4] Leguen MA. Single-blind clinical trial comparing use of fentiazac and paracetamol in postendodontic periodontitis. Clin Ther. 1985;7(2):145-50. PubMed PMID: 3886139.

[5] Thumb N, Kolarz G, Scherak O, Mayrhofer F. The efficacy and safety of fentiazac and diclofenac sodium in peri-arthritis of the shoulder: a multi-centre, double-blind comparison. J Int Med Res. 1987 Nov-Dec;15(6):327-34. PubMed PMID: 3325316.

6: Catti A. Controlled clinical study with Fentiazac suspension in painful inflammatory diseases of children. J Int Med Res. 1983;11(5):298-302. PubMed PMID: 6605890.7: Famaey JP, Gaci O, Ginsberg F. Fentiazac in the treatment of osteoarthritis and tendinitis. Curr Med Res Opin. 1983;8(9):675-81. PubMed PMID: 6365468.8: Fumero S, Mondino A, Silvestri S, Zanolo G, De Marchi G, Pedrazzini S. Metabolism of fentiazac. Arzneimittelforschung. 1980;30(8):1253-6. PubMed PMID: 7192138.9: López Rosales C, Cisneros Lugo JH, Romo Enciso LJ, García Sandoval MG. [Nimesulide in the treatment of primary dysmenorrhea. Comparative clinical evaluation with mefenamic acid and fentiazac]. Ginecol Obstet Mex. 1989 Jul;57:196-201. Spanish. PubMed PMID: 2486951.10: López JM. Treatment of acute tendinitis and bursitis with fentiazac--a double-blind comparison with placebo. Clin Ther. 1982;5(1):79-84. PubMed PMID: 6751536.1

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