29050-11-1|Seclazone|2H,9H-Isoxazolo(3,2-b)(1,3)benzoxazin-9-one, 3,3a-dihydro-7-chloro-|-范德生物科技公司

Seclazone

NMR下载 COA and HPLC MSDS下载
names：
2H,9H-Isoxazolo(3,2-b)(1,3)benzoxazin-9-one, 3,3a-dihydro-7-chloro-
CAS号：
29050-11-1
MDL Number：
MF(分子式)： C10H8ClNO3 MW(分子量)： 225.628
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	2H,9H-Isoxazolo(3,2-b)(1,3)benzoxazin-9-one, 3,3a-dihydro-7-chloro-
英文别名	Seclazone; W-2354; W 2354; W2354; W 2352;
CAS号	29050-11-1
SMILES	O=C1N(OCC2)C2OC3=CC=C(Cl)C=C13
Inchi	InChI=1S/C10H8ClNO3/c11-6-1-2-8-7(5-6)10(13)12-9(15-8)3-4-14-12/h1-2,5,9H,3-4H2
InchiKey	XWXVKXXKKLBDDJ-UHFFFAOYSA-N
分子式 Formula	C10H8ClNO3
分子量 Molecular Weight	225.628
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Seclazone(CAS:29050-11-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Seclazone is a biochemical.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Viaje A, Slaga TJ, Wigler M, Weinstein IB. Effects of antiinflammatory agents on mouse skin tumor promotion, epidermal DNA synthesis, phorbol ester-induced cellular proliferation, and production of plasminogen activator. Cancer Res. 1977 May;37(5):1530-6. PubMed PMID: 856468.

[2]Slaga TJ, Viaje A, Bracken W. The effects of anti-inflammatory agents on skin tumor initiation and aryl hydrocarbon hydroxylase. Res Commun Chem Pathol Pharmacol. 1977 Feb;16(2):337-50. PubMed PMID: 847288.

[3] Edelson J, Schuster EB, Douglas JF. Optimal conditions for the hydrolysis of seclazone by rat hepatic microsomes. Arch Int Pharmacodyn Ther. 1974 Sep;211(1):99-106. PubMed PMID: 4218724.

[4] Edelson J, Schuster E, Shahinian S, Douglas JF. The metabolic fate of seclazone in man. Arch Int Pharmacodyn Ther. 1974 May;209(1):66-74. PubMed PMID: 4416360.

[5] Edelson J, Douglas JF, Ludwig BJ. Seclazone: biotransformation during absorption in the rat, binding in plasma, and disappearance from plasma in the dog. Drug Metab Dispos. 1973 Nov-Dec;1(6):737-41. PubMed PMID: 4156294.

6: Edelson J, Douglas JF, Ludwig BJ. Absorption, distribution, and metabolic fate of seclazone (7-chloro-3,3a-dihydro-2H,9H-isoxazolo(3,2-b) (1,3)benzoxazin-9-one). J Pharm Sci. 1973 Feb;62(2):229-32. PubMed PMID: 4631323.7: Edelson J, Douglas JF. Measurement of gastrointestinal blood loss in the rat: the effect of aspirn, phenylbutazone and seclazone. J Pharmacol Exp Ther. 1973 Feb;184(2):449-52. PubMed PMID: 4540048.8: Hrdina PD, Ling GM. The in vivo antibradykinin activity of seclazone (7-chloro-3,3a-dihydro-2H,9H-isoxazolo(3,2-b) (1,3)benzoxazin-9-one), a new anti-inflammatory agent. Pharmacology. 1973;10(3):136-42. PubMed PMID: 4761775.9: Berger FM, Bates HM, Diamantis W, Kletzkin M, Plekss OJ, Sofia RD, Spencer HJ. The pharmacological properties of seclazone (7-chloro-3,3a-dihydro-2H, 9H-isoxazolo (3,2-b) (1,3) benzoxazin-9-one) a new anti-inflammatory agent. Pharmacology. 1973;9(3):164-76. PubMed PMID: 4714232.

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