26012-92-0|Scoytr|1H-Cyclodec(e)indene-3,6,9(2H)-trione, 11,12-didehydro-3a,4,5,5a,7,8,10,13,13a,13b-decahydro-3a-methyl-, (3aS-(3aR*,5aR*,13aR*,13bR*))-|-范德生物科技公司

Scoytr

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names：
1H-Cyclodec(e)indene-3,6,9(2H)-trione, 11,12-didehydro-3a,4,5,5a,7,8,10,13,13a,13b-decahydro-3a-methyl-, (3aS-(3aR*,5aR*,13aR*,13bR*))-
CAS号：
26012-92-0
MDL Number：
MF(分子式)： C18H22O3 MW(分子量)： 286.371
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	1H-Cyclodec(e)indene-3,6,9(2H)-trione, 11,12-didehydro-3a,4,5,5a,7,8,10,13,13a,13b-decahydro-3a-methyl-, (3aS-(3aR,5aR,13aR,13bR))-
英文别名	5,10-Secoestr-4-yne-3,10,17-trione; Scoytr
CAS号	26012-92-0
SMILES	O=C1CC[C@@]2([H])[C@@]3([H])[C@](C(CCC(CC#CC3)=O)=O)([H])CC[C@]12C
Inchi	InChI=1S/C18H22O3/c1-18-11-10-14-13(15(18)7-9-17(18)21)5-3-2-4-12(19)6-8-16(14)20/h13-15H,4-11H2,1H3/t13-,14+,15+,18+/m1/s1
InchiKey	PREVPDQOQFQBKT-LLDVTBCESA-N
分子式 Formula	C18H22O3
分子量 Molecular Weight	286.371
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Scoytr(CAS:26012-92-0):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Scoytr is a peptide associated with the isomerase activity of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Thomas JL, Evans BW, Strickler RC. Affinity radiolabeling identifies peptides associated with the isomerase activity of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase. Biochemistry. 1997 Jul 22;36(29):9029-34. PubMed PMID: 9220991.

[2]Thomas JL, Strickler RC, Myers RP, Covey DF. Affinity labeling of human placental 3 beta-hydroxy-delta 5-steroid dehydrogenase and steroid delta-isomerase: evidence for bifunctional catalysis by a different conformationof the same protein for each enzyme activity. Biochemistry. 1992 Jun 23;31(24):5522-7. PubMed PMID: 1610797.

[3] Penning TM, Heller DN, Balasubramanian TM, Fenselau CC, Talalay P. Mass spectrometric studies of a modified active-site tetrapeptide from delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni. J Biol Chem. 1982 Nov 10;257(21):12589-93. PubMed PMID: 7130168.

[4] Penning TM, Covey DF. Inactivation of delta 5-3-ketosteroid isomerase(s) from beef adrenal cortex by acetylenic ketosteroids. J Steroid Biochem. 1982 May;16(5):691-9. PubMed PMID: 7098483.

[5] Penning TM. Inactivation of delta5-3-ketosteroid isomerase(s) from beef adrenal cortex by beta, gamma-acetylenic ketosteroids. Steroids. 1982 Mar;39(3):301-11. PubMed PMID: 7090026.

6: Penning TM, Covey DF, Talalay P. Irreversible inactivation of delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni by acetylenic suicide substrates. Mechanism of formation and properties of the steroid-enzyme adduct. J Biol Chem. 1981 Jul 10;256(13):6842-50. PubMed PMID: 7240247.7: Penning TM, Talalay P. Linkage of an acetylenic secosteroid suicide substrate to the active site of delta 5-3-ketosteroid isomerase. Isolation and characterization of a tetrapeptide. J Biol Chem. 1981 Jul 10;256(13):6851-8. PubMed PMID: 7016878.8: Penning TM, Westbrook EM, Talalay P. On the number of steroid-binding sites of delta 5-3-oxosteroid isomerase. Eur J Biochem. 1980 Apr;105(3):461-9. PubMed PMID: 7371643.

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