26012-92-0|Scoytr|1H-Cyclodec(e)indene-3,6,9(2H)-trione, 11,12-didehydro-3a,4,5,5a,7,8,10,13,13a,13b-decahydro-3a-methyl-, (3aS-(3aR*,5aR*,13aR*,13bR*))-|-范德生物科技公司

Scoytr

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names：
1H-Cyclodec(e)indene-3,6,9(2H)-trione, 11,12-didehydro-3a,4,5,5a,7,8,10,13,13a,13b-decahydro-3a-methyl-, (3aS-(3aR*,5aR*,13aR*,13bR*))-
CAS号：
26012-92-0
MDL Number：
MF(分子式)： C18H22O3 MW(分子量)： 286.371
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	1H-Cyclodec(e)indene-3,6,9(2H)-trione, 11,12-didehydro-3a,4,5,5a,7,8,10,13,13a,13b-decahydro-3a-methyl-, (3aS-(3aR,5aR,13aR,13bR))-
英文别名	5,10-Secoestr-4-yne-3,10,17-trione; Scoytr
CAS号	26012-92-0
Inchi	InChI=1S/C18H22O3/c1-18-11-10-14-13(15(18)7-9-17(18)21)5-3-2-4-12(19)6-8-16(14)20/h13-15H,4-11H2,1H3/t13-,14+,15+,18+/m1/s1
InchiKey	PREVPDQOQFQBKT-LLDVTBCESA-N
分子式 Formula	C18H22O3
分子量 Molecular Weight	286.371
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Scoytr(CAS:26012-92-0):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Scoytr is a peptide associated with the isomerase activity of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
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备注

[1]Thomas JL, Evans BW, Strickler RC. Affinity radiolabeling identifies peptides associated with the isomerase activity of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase. Biochemistry. 1997 Jul 22;36(29):9029-34. PubMed PMID: 9220991.

[2]Thomas JL, Strickler RC, Myers RP, Covey DF. Affinity labeling of human placental 3 beta-hydroxy-delta 5-steroid dehydrogenase and steroid delta-isomerase: evidence for bifunctional catalysis by a different conformationof the same protein for each enzyme activity. Biochemistry. 1992 Jun 23;31(24):5522-7. PubMed PMID: 1610797.

[3] Penning TM, Heller DN, Balasubramanian TM, Fenselau CC, Talalay P. Mass spectrometric studies of a modified active-site tetrapeptide from delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni. J Biol Chem. 1982 Nov 10;257(21):12589-93. PubMed PMID: 7130168.

[4] Penning TM, Covey DF. Inactivation of delta 5-3-ketosteroid isomerase(s) from beef adrenal cortex by acetylenic ketosteroids. J Steroid Biochem. 1982 May;16(5):691-9. PubMed PMID: 7098483.

[5] Penning TM. Inactivation of delta5-3-ketosteroid isomerase(s) from beef adrenal cortex by beta, gamma-acetylenic ketosteroids. Steroids. 1982 Mar;39(3):301-11. PubMed PMID: 7090026.

6: Penning TM, Covey DF, Talalay P. Irreversible inactivation of delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni by acetylenic suicide substrates. Mechanism of formation and properties of the steroid-enzyme adduct. J Biol Chem. 1981 Jul 10;256(13):6842-50. PubMed PMID: 7240247.7: Penning TM, Talalay P. Linkage of an acetylenic secosteroid suicide substrate to the active site of delta 5-3-ketosteroid isomerase. Isolation and characterization of a tetrapeptide. J Biol Chem. 1981 Jul 10;256(13):6851-8. PubMed PMID: 7016878.8: Penning TM, Westbrook EM, Talalay P. On the number of steroid-binding sites of delta 5-3-oxosteroid isomerase. Eur J Biochem. 1980 Apr;105(3):461-9. PubMed PMID: 7371643.

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