1508-76-5|Procyclidine Hydrochloride|1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol;hydrochloride|-范德生物科技公司

Procyclidine Hydrochloride

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names：
1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol;hydrochloride
CAS号：
1508-76-5
MDL Number：
MF(分子式)： C19H30ClNO MW(分子量)： 323.9
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol;hydrochloride
英文别名	Procyclidine Hydrochloride; Procyclidine HCl; Tricyclamol hydrochloride; (-)-Tricyclamol iodide; C19H29NO.HCl; Procyclidine Hydrochloride; Rosemont Brand of Procyclidine Hydrochloride; Tricyclamol; Wellcome Brand of Procyclidine Hydrochloride;
CAS号	1508-76-5
SMILES	C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O.Cl
Inchi	InChI=1S/C19H29NO.ClH/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20;/h1,3-4,9-10,18,21H,2,5-8,11-16H2;1H
InchiKey	ZFSPFXJSEHCTTR-UHFFFAOYSA-N
分子式 Formula	C19H30ClNO
分子量 Molecular Weight	323.9
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Procyclidine Hydrochloride(CAS:1508-76-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Procyclidine hydrochloride is a muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in Parkinsonism.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Campbell MJ, Demetriou B, Jones R. Assay of procyclidine hydrochloride,cyclizine hydrochloride and diethylcarbamazine citrate in tablets usingion-responsive electrodes. Analyst. 1980 Jun;105(1251):605-1[1]PubMed PMID:7416480.

[2]Camerman N, Camerman A. The stereochemical basis of anticonvulsant drugaction. 3. The structure of procyclidine hydrochloride. Mol Pharmacol. 1971Jul;7(4):406-12. PubMed PMID: 5113235.

[3] RENZI AA, MILCH LJ. Effectiveness of procyclidine hydrochloride (kemadrin) andcycrimine hydrochloride (pagitane) in the prevention of airsickness. J Aviat Med.1958 Aug;29(8):587-9. PubMed PMID: 13575361.

[4] ZIER A, DOSHAY LJ. Procyclidine hydrochloride (kemadrin) treatment ofparkinsonism; result in 108 patients. Neurology. 1957 Jul;7(7):485-9. PubMedPMID: 13451881.

[5] Schjelderup L, Harbitz O, Groth P, Aasen AJ. Syntheses of(S)-(+)-trihexyphenidyl hydrochloride and (S)-(+)-procyclidine hydrochloride, twoanticholinergics, using (S)-(-)-3-cyclohexyl-3-hydroxy-3-phenylpropanoic acid aschiral synthon. Acta Chem Scand B. 1987 May;41(5):356-61. PubMed PMID: 3673449.

6: Meier V. [Poisoning with procyclidine hydrochloride (Kemadrin)]. SchweizRundsch Med Prax. 1973 Apr 10;62(15):473-5. German. PubMed PMID: 4695200.7: Vas CJ, Exley KA, Parsonage MJ. Activation of the EEG by procyclidinehydrochloride in temporal lobe epilepsy. Epilepsia. 1967 Dec;8(4):241-51. PubMedPMID: 5238716.8: Vas CJ, Exley KA, Parsonage MJ. EEG activation by procyclidine hydrochloridein temporal lobe epilepsy. Electroencephalogr Clin Neurophysiol. 1967Apr;22(4):395. PubMed PMID: 4164765.9: GROSS H, LANGNER E. [Prophylaxis and therapy of a drug-related Parkinsonsyndrome with procyclidine hydrochloride (Kemadrin)]. Wien Klin Wochenschr. 1962Aug 31;7

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