110143-10-7|Lodenosine|((2S,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluorotetrahydrofuran-2-yl)methanol|-范德生物科技公司

Lodenosine

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names：
((2S,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluorotetrahydrofuran-2-yl)methanol
CAS号：
110143-10-7
MDL Number：
MF(分子式)： C10H12FN5O2 MW(分子量)： 253.2374
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Lodenosine
英文别名	Lodenosine; 2'-F-dd-ara-A; 2'-Fluoro-2'; 3'-dideoxyarabinosyladenine; DDG-1; FddA; Fddl; NSC-613792.
CAS号	110143-10-7
SMILES	OC[C@H]1O[C@@H](N2C=NC3=C(N)N=CN=C23)[C@@H](F)C1
Inchi	InChI=1S/C10H12FN5O2/c11-6-1-5(2-17)18-10(6)16-4-15-7-8(12)13-3-14-9(7)16/h3-6,10,17H,1-2H2,(H2,12,13,14)/t5-,6-,10+/m0/s1
InchiKey	KBEMFSMODRNJHE-JFWOZONXSA-N
分子式 Formula	C10H12FN5O2
分子量 Molecular Weight	253.2374
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Lodenosine(CAS:110143-10-7):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Lodenosine, also known as DDG-1; FddA; Fddl; NSC-613792, is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Bei N, Li G, Meng Z, Weng Y, Zavala M, Molina LT. Impacts of using an ensemble Kalman filter on air quality simulations along the California-Mexico border region during Cal-Mex 2010 field campaign. Sci Total Environ. 2014 Nov 15;499:141-53. doi: 10.1016/j.scitotenv.2014.07.12[1]PubMed PMID: 25181046.

[2]Rahman Z, MacFalls H, Jiang K, Chan KF, Kelly K, Tournas J, Stumpp OF, Bedi V, Zachary C. Fractional deep dermal ablation induces tissue tightening. Lasers Surg Med. 2009 Feb;41(2):78-86. doi: 10.1002/lsm.20715. PubMed PMID: 19226572.

[3] Katayama S, Takamatsu S, Hirose N, Izawa K, Maruyama T. Synthesis of fluorinated nucleosides. Curr Protoc Nucleic Acid Chem. 2006 Jul;Chapter 1:Unit 1.12. doi: 10.1002/0471142700.nc0112s25. PubMed PMID: 18428944.

[4] Saravanan G, Ozeki S. Magnetic field control of electron tunneling pathways in the monolayer of (ferrocenylmethyl)dodecyldimethylammonium bromide on a gold electrode. J Phys Chem B. 2008 Jan 10;112(1):3-6. PubMed PMID: 18076154.

[5] Izawa K, Takamatsu S, Katayama S, Hirose N, Kozai S, Maruyama T. An industrial process for synthesizing Lodenosine (FddA). Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):507-17. PubMed PMID: 14565226.

6: Maruyama T, Kozai S, Takamatsu S, Izawa K. Introduction of a benzoyl group onto 6-chloropurine riboside in aqueous solution and its application to the synthesis of nucleoside derivatives. Nucleic Acids Symp Ser. 2000;(44):103-4. PubMed PMID: 12903289.7: Mendoza-Dominguez A, Russell AG. Emission strength validation using four-dimensional data assimilation: application to primary aerosol and precursors to ozone and secondary aerosol. J Air Waste Manag Assoc. 2001 Nov;51(11):1538-50. PubMed PMID: 11720101.8: Takamatsu S, Maruyama T, Katayama S, Hirose N, Naito M, Izawa K. Synthesis of 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)adenine (FddA) via a purine 3'-deoxynucleoside. J Org Chem. 2001 Nov 2;66(22):7469-77. PubMed PMID: 11681963.9: Luy B, Barchi JJ Jr, Marino JP. S(3)E-E.COSY methods for the measurement of (19)F associated scalar and dipolar coupling constants. J Magn Reson. 2001 Sep;152(1):179-84. PubMed PMID: 11531377.10: Antiretroviral update from the Interscience Conference on Antimicrobial Agents and Chemotherapy. Newsline People AIDS Coalit N Y. 1998 Dec:16-8. PubMed PMID: 11367083.1

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