1703-31-7|LG 50042|2,6-dimethoxy-4-(morpholine-4-carbonyl)phenyl ethyl carbonate|-范德生物科技公司

LG 50042

NMR下载 COA and HPLC MSDS下载
names：
2,6-dimethoxy-4-(morpholine-4-carbonyl)phenyl ethyl carbonate
CAS号：
1703-31-7
MDL Number：
MF(分子式)： C16H21NO7 MW(分子量)： 339.34
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	LG 50042
英文别名	LG 50042; LG-50042; LG50042; LG 50,042; LG-50,042; LG50,042;
CAS号	1703-31-7
SMILES	O=C(N1CCOCC1)C2=CC(OC)=C(OC(OCC)=O)C(OC)=C2
Inchi	InChI=1S/C16H21NO7/c1-4-23-16(19)24-14-12(20-2)9-11(10-13(14)21-3)15(18)17-5-7-22-8-6-17/h9-10H,4-8H2,1-3H3
InchiKey	SFVJZJHVCCHUGR-UHFFFAOYSA-N
分子式 Formula	C16H21NO7
分子量 Molecular Weight	339.34
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	LG 50042(CAS:1703-31-7):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	LG 50042 is a bioactive chemical.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Andreassen KV, Feigh M, Hjuler ST, Gydesen S, Henriksen JE, Beck-Nielsen H, Christiansen C, Karsdal MA, Henriksen K. A novel oral dual amylin and calcitonin receptor agonist (KBP-042) exerts antiobesity and antidiabetic effects in rats. Am J Physiol Endocrinol Metab. 2014 Jul 1;307(1):E24-33. doi: 10.1152/ajpendo.00121.2014. Epub 2014 May 6. PubMed PMID: 24801386.

[2]Hjuler ST, Andreassen KV, Gydesen S, Karsdal MA, Henriksen K. KBP-042 improves bodyweight and glucose homeostasis with indices of increased insulin sensitivity irrespective of route of administration. Eur J Pharmacol. 2015 Sep 5;76

2:229-38. doi: 10.1016/j.ejphar.2015.05.051. Epub 2015 May 28. PubMed PMID: 26027795.

[4]Arakawa K, Maehara S, Yuge N, Ishikawa M, Miyazaki Y, Naba H, Kato Y, Nakao K. Pharmacological characterization of a novel potent, selective, and orally active phosphodiesterase 10A inhibitor, PDM-042 [(E)-4-(2-(2-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)vinyl)-6-(pyrrolidi n-1-yl)pyrimidin-4-yl)morpholine] in rats: potential for the treatment of schizophrenia. Pharmacol Res Perspect. 2016 Jun 10;4(4):e00241. doi: 10.1002/prp2.241. eCollection 2016 Aug. PubMed PMID: 28116094; PubMed Central PMCID: PMC5242175.

[5] Miyake T, Honma Y, Urano T, Kato N, Suzumiya J. Combined treatment with tamoxifen and a fusicoccin derivative (ISIR-042) to overcome resistance to therapy and to enhance the antitumor activity of 5-fluorouracil and gemcitabine in pancreatic cancer cells. Int J Oncol. 2015 Jul;47(1):315-24. doi: 10.3892/ijo.2015.2979. Epub 2015 Apr 30. PubMed PMID: 25936828.

5: Hjuler ST, Gydesen S, Andreassen KV, Pedersen SL, Hellgren LI, Karsdal MA, Henriksen K. The dual amylin- and calcitonin-receptor agonist KBP-042 increases insulin sensitivity and induces weight loss in rats with obesity. Obesity (Silver Spring). 2016 Aug;24(8):1712-22. doi: 10.1002/oby.21563. Epub 2016 Jun 14. PubMed PMID: 27296301.

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