58298-76-3|Jatrophatrione|(3aR,9R,10aS,11aS,Z)-3,3,6,9,11a-pentamethyl-2,3,3a,10,10a,11a-hexahydro-1H-dicyclopenta[a,d][9]annulene-1,5,11(4H,9H)-trione|-范德生物科技公司

Jatrophatrione

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names：
(3aR,9R,10aS,11aS,Z)-3,3,6,9,11a-pentamethyl-2,3,3a,10,10a,11a-hexahydro-1H-dicyclopenta[a,d][9]annulene-1,5,11(4H,9H)-trione
CAS号：
58298-76-3
MDL Number：
MF(分子式)： C20H26O3 MW(分子量)： 314.42
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Jatrophatrione
英文别名	Jatrophatrione; NSC 254668; NSC-254668; NSC254668;
CAS号	58298-76-3
Inchi	InChI=1S/C20H26O3/c1-11-6-13-8-12(2)15(21)9-16-19(3,4)10-17(22)20(16,5)18(23)14(13)7-11/h6,8,11,14,16H,7,9-10H2,1-5H3/b12-8-/t11-,14-,16+,20-/m0/s1
InchiKey	TYBGBKQPLBAYQG-CJIMKZOCSA-N
分子式 Formula	C20H26O3
分子量 Molecular Weight	314.42
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Jatrophatrione(CAS:58298-76-3):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Jatrophatrione is a bioactive mesotricyclic diterpenoid.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Melchor-Martínez EM, Silva-Mares DA, Torres-López E, Waksman-Minsky N, Pauli GF, Chen SN, Niemitz M, Sánchez-Castellanos M, Toscano A, Cuevas G, Rivas-Galindo VM. Stereochemistry of a Second Riolozane and Other Diterpenoids from Jatropha dioica. J Nat Prod. 2017 Aug 25;80(8):2252-2262. doi: 10.1021/acs.jnatprod.7b00193. Epub 2017 Aug 3. PubMed PMID: 28771358; PubMed Central PMCID: PMC5714812.

[2]Yang J, Long YO, Paquette LA. Concise total syntheses of the bioactive mesotricyclic diterpenoids jatrophatrione and citlalitrione. J Am Chem Soc. 2003 Feb 12;125(6):1567-74. PubMed PMID: 12568617.

[3] Paquette LA, Yang J, Long YO. Concerning the antileukemic agent jatrophatrione: the first total synthesis of a [5.9.5] tricyclic diterpene. J Am Chem Soc. 2002 Jun 12;124(23):6542-3. PubMed PMID: 12047168.

[4] Paquette LA, Edmondson SD, Monck N, Rogers RD. Studies Directed toward the Synthesis of the Unusual Antileukemic Diterpene Jatrophatrione. 2. Functionalization of Advanced Polycyclic Precursors to the 9-Epi and 8,9-Dehydro Congeners. J Org Chem. 1999 Apr 30;64(9):3255-3265. PubMed PMID: 11674428.

[5] Paquette LA, Nakatani S, Zydowsky TM, Edmondson SD, Sun LQ, Skerlj R. Studies Directed toward the Synthesis of the Unusual Antileukemic Diterpene Jatrophatrione. 1. A Solution to the Problem of Chirality Merger during Elaboration of the Entire Carbotricyclic Framework. J Org Chem. 1999 Apr 30;64(9):3244-3254. PubMed PMID: 11674427.

6: Torrance SJ, Wiedhopf RM, Cole JR, Arora SK, Bates RB, Beavers WA, Cutler RS. Antitumor agents from Jatropha macrorhiza (Euphorbiaceae). II. Isolation and characterization of jatrophatrione. J Org Chem. 1976 May 14;41(10):1855-7. PubMed PMID: 1262992.

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