77026-81-4|DN 1417|(2S)-1-((5-oxotetrahydrofuran-2-carbonyl)-L-histidyl)pyrrolidine-2-carboxamide 2-hydroxypropane-1,2,3-tricarboxylate|-范德生物科技公司

DN 1417

NMR下载 COA and HPLC MSDS下载
names：
(2S)-1-((5-oxotetrahydrofuran-2-carbonyl)-L-histidyl)pyrrolidine-2-carboxamide 2-hydroxypropane-1,2,3-tricarboxylate
CAS号：
77026-81-4
MDL Number：
MF(分子式)： C22H29N5O12 MW(分子量)： 555.49
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)

大包装询价提供各种包装，敬请垂询
收藏商品商品点评加入购物车立即购买

快速询价

收起

你想询价的产品

*产品名称：

CAS号：

产品编号：

需求描述：

请准确填写您的联系方式，以便为您提供最好的服务。

*公司名称：

*电子邮箱：

联系人：

*电话：

*验证码：

询价

中文别名	DN 1417
英文别名	DN 1417; DN-1417; DN1417;
CAS号	77026-81-4
SMILES	O=C(N)[C@H]1N(C([C@H](CC2=CNC=N2)NC(C(CC3)OC3=O)=O)=O)CCC1.O=C(CC(C(O)=O)(O)CC(O)=O)O
Inchi	InChI=1S/C16H21N5O5.C6H8O7/c17-14(23)11-2-1-5-21(11)16(25)10(6-9-7-18-8-19-9)20-15(24)12-3-4-13(22)26-12;7-3(8)1-6(13,5(11)12)2-4(9)10/h7-8,10-12H,1-6H2,(H2,17,23)(H,18,19)(H,20,24);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t10-,11-,12?;/m0./s1
InchiKey	YYPBZNVNEDBLON-MEMPEZCVSA-N
分子式 Formula	C22H29N5O12
分子量 Molecular Weight	555.49
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	DN 1417(CAS:77026-81-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	DN 1417 is a thyrotropin releasing hormone analog.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Nakahara T, Matsumoto T, Hirano M, Uchimura H, Yokoo H, Nakamura K, Ishibashi K, Hirano H. Effect of DN-1417, a thyrotropin releasing hormone analog, on dopaminergic neurons in rat brain. Peptides. 1985 Nov-Dec;6(6):1093-9. PubMed PMID: 3938840.

[2]Oshima I, Saito S, Shiota K, Miyake A, Oka Y, Nakayama R. Kinetic study on disappearance of gamma-butyrolactone-gamma-carbonyl-L-histidyl-L-prolinamide (DN-1417) from plasma using a radioimmunoassay for DN-1417 isobutylamide. J Pharmacobiodyn. 1983 Mar;6(3):202-8. PubMed PMID: 6410041.

[3] Mori N, Fukatsu T. Anticonvulsant effect of DN-1417, a derivative of thyrotropin-releasing hormone, and liposome-entrapped DN-1417, on amygdaloid-kindled rats. Epilepsia. 1992 Nov-Dec;33(6):994-1000. PubMed PMID: 1464282.

[4] Sakai S, Baba H, Sato M, Wada JA. Effect of DN-1417 on photosensitivity and cortically kindled seizure in Senegalese baboons, Papio papio. Epilepsia. 1991 Jan-Feb;32(1):16-21. PubMed PMID: 1898719.

[5] Hawley RJ, Kratz R, Goodman RR, McCutchen CB, Sirdofsky M, Hanson PA. Treatment of amyotrophic lateral sclerosis with the TRH analog DN-1417. Neurology. 1987 Apr;37(4):715-7. PubMed PMID: 3104820.

6: Mizuki Y, Ushijima I, Yamada M, Tanaka M, Inanaga K. A treatment trial with an analog of thyrotropin-releasing hormone (DN-1417) and des-tyrosine-gamma-endorphin in schizophrenia. Int Clin Psychopharmacol. 1986 Oct;1(4):303-13. PubMed PMID: 2881964.7: Nagai Y, Narumi S, Saji Y, Nagawa Y. [A TRH analog (DN-1417). Antagonistic effects on reserpine-induced decreases in local cerebral glucose utilization and cerebral monoamine levels]. Nihon Yakurigaku Zasshi. 1985 May;85(5):315-26. Japanese. PubMed PMID: 3928465.8: Nagai Y, Narumi S, Miyamoto M, Shima T, Saji Y, Nagawa Y. [A TRH analog (DN-1417). Effects on the levels of monoamines and the metabolites in the various brain regions in rats]. Nihon Yakurigaku Zasshi. 1985 Apr;85(4):209-20. Japanese. PubMed PMID: 3924795.9: Ogawa T, Moriwake T, Morimoto K, Sato M, Otsuki S. [The effect of a novel TRH analog (DN-1417) on postictal seizure inhibition in amygdaloid kindled cats]. No To Shinkei. 1984 Oct;36(10):951-5. Japanese. PubMed PMID: 6440585.10: Yokoo H, Nakahara T, Matsumoto T, Inanaga K, Uchimura H. Effect of TRH analog (DN-1417) on tyrosine hydroxylase activity in mesocortical, mesolimbic and nigrostriatal dopaminergic neurons of rat brain. Peptides. 1987 Jan-Feb;8(1):49-53. PubMed PMID: 2883633.1

对不起，暂无产品评价！

MSDS

SDS 1.0 中文

展开

SDS 1.0 英文

展开