85287-61-2|Cefpimizole sodium|Pyridinium, 1-((2-carboxy-7-(((((5-carboxy-1H-imidazol-4-yl)carbonyl)amino)phenylacetyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-4-(2-sulfoethyl)-, hydroxide, inner salt, monosodium salt, (6R-(6alpha,7beta(R*)))-|-范德生物科技公司

Cefpimizole sodium

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names：
Pyridinium, 1-((2-carboxy-7-(((((5-carboxy-1H-imidazol-4-yl)carbonyl)amino)phenylacetyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-4-(2-sulfoethyl)-, hydroxide, inner salt, monosodium salt, (6R-(6alpha,7beta(R*)))-
CAS号：
85287-61-2
MDL Number：
MF(分子式)： C28H25N6NaO10S2 MW(分子量)： 692.65
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Cefpimizole sodium
英文别名	Cefpimizole sodium; AC 1370 sodium; AC 1370; AC-1370; AC1370
CAS号	85287-61-2
Inchi	InChI=1S/C28H26N6O10S2.Na/c35-23(18(16-4-2-1-3-5-16)31-24(36)19-20(27(38)39)30-14-29-19)32-21-25(37)34-22(28(40)41)17(13-45-26(21)34)12-33-9-6-15(7-10-33)8-11-46(42,43)44;/h1-7,9-10,14,18,21,26H,8,11-13H2,(H5-,29,30,31,32,35,36,38,39,40,41,42,43,44);/q;+1/p-1/t18?,21-,26-;/m0./s1
InchiKey	JLUNZNNMKVKUOH-YKGHYQGCSA-M
分子式 Formula	C28H25N6NaO10S2
分子量 Molecular Weight	692.65
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Cefpimizole sodium(CAS:85287-61-2):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Cefpimizole sodium is a Semisynthetic cephalosporin. It is an Antibacterial.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Periti P. Immunopharmacology of oral betalactams. J Chemother. 1998 Apr;10(2):91-6. Review. PubMed PMID: 9603632.

[2]Toyoguchi T, Nakagawa Y. [Nephrotoxicity and drug interaction of vancomycin (2)]. Nihon Yakurigaku Zasshi. 1996 May;107(5):225-35. Japanese. PubMed PMID: 8690304.

[3] Araki A, Sendo F. Reduced anti-Pseudomonas aeruginosa activity of a cephalosporin, cefodizime, in rats whose neutrophils were selectively depleted by a monoclonal antibody. Microbiol Immunol. 1996;40(5):333-8. PubMed PMID: 8999285.

[4] Ueta E, Yoneda K, Yamamoto T, Osaki T. Upregulatory effects of cefpimizole natrium on human leukocytes. Int J Immunopharmacol. 1992 Jul;14(5):877-85. PubMed PMID: 1324894.

[5] Nagano T, Ueno T, Mukai K, Yano S. [Case posing a therapeutic problem due to gastrointestinal hemorrhage caused by a factor VIII inhibitor following antibiotic administration]. Nihon Naika Gakkai Zasshi. 1991 Apr 10;80(4):619-20. Japanese. PubMed PMID: 1905741.

6: Ito K, Hayasaki M, Tamaya T. Pharmacokinetics of cephem antibiotics in exudate of pelvic retroperitoneal space after radical hysterectomy and pelvic lymphadenectomy. Antimicrob Agents Chemother. 1990 Jun;34(6):1160-4. PubMed PMID: 2393276; PubMed Central PMCID: PMC171777.7: Oishi K, Matsumoto K, Yamamoto M, Morito T, Yoshida T. Stimulatory effect of cefodizime on macrophage-mediated phagocytosis. J Antibiot (Tokyo). 1989 Jun;42(6):989-92. PubMed PMID: 2737956.8: Raad II, Sherertz RJ, Loveless MO, Carillo C, O'Connor RP, Miller M, Mostow SR. Comparison of cefpimizole with cefotaxime and penicillin G for treatment of uncomplicated gonorrhea. Sex Transm Dis. 1988 Apr-Jun;15(2):73-7. PubMed PMID: 3041630.9: Sato K, Saito H, Tomioka H. [In vitro and in vivo antimycobacterial activities of cefpimizole (AC-1370) and its effect on oxygen metabolism of host macrophages]. Kekkaku. 1988 Jan;63(1):19-25. Japanese. PubMed PMID: 3361739.10: Koga H. High-performance liquid chromatography measurement of antimicrobial concentrations in polymorphonuclear leukocytes. Antimicrob Agents Chemother. 1987 Dec;31(12):1904-8. PubMed PMID: 3439800; PubMed Central PMCID: PMC175825.1

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