17598-65-1|Deslanosid|Deslanosid|-范德生物科技公司

Deslanosid

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names：
Deslanosid
CAS号：
17598-65-1
MDL Number：
MF(分子式)： C47H74O19 MW(分子量)： 943.09
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	4-((3S,5R,8R,9S,10S,12R,13S,14S,17R)-12,14-dihydroxy-3-(((2R,4S,5S,6R)-4-hydroxy-5-(((2S,4S,5S,6R)-4-hydroxy-5-(((2S,4S,5S,6R)-4-hydroxy-6-methyl-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one
英文别名	Deslanosid; Ceglunat; Lekozid; Lanatosid C; Sediranido;
CAS号	17598-65-1
SMILES	O=C1OCC([C@H]2CC[C@]3(O)[C@]4([H])CC[C@]5([H])C[C@@H](O[C@H]6C[C@@H]([C@@H]([C@@H](C)O6)O[C@H]7C[C@@H]([C@@H]([C@@H](C)O7)O[C@H]8C[C@@H]([C@@H]([C@@H](C)O8)O[C@H]9[C@@H]([C@H]([C@@H]([C@@H](CO)O9)O)O)O)O)O)O)CC[C@]5(C)[C@@]4([H])C[C@@H](O)[C@]23C)=C1
Inchi	InChI=1S/C47H74O19/c1-20-41(64-36-16-30(50)42(21(2)60-36)65-37-17-31(51)43(22(3)61-37)66-44-40(56)39(55)38(54)32(18-48)63-44)29(49)15-35(59-20)62-25-8-10-45(4)24(13-25)6-7-27-28(45)14-33(52)46(5)26(9-11-47(27,46)57)23-12-34(53)58-19-23/h12,20-22,24-33,35-44,48-52,54-57H,6-11,13-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,33-,35+,36+,37+,38-,39+,40-,41-,42-,43-,44+,45+,46+,47+/m1/s1
InchiKey	OBATZBGFDSVCJD-LALPQLPRSA-N
分子式 Formula	C47H74O19
分子量 Molecular Weight	943.09
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Deslanosid(CAS:17598-65-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Deslanosid is a cardiotonic glycoside from the leaves of Digitalis lanata.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Chen DP, Xiong YJ, Tang ZY, Yao QY, Ye DM, Liu SS, Lin Y. Characteristics of deslanoside-induced modulation on jejunal contractility. World J Gastroenterol. 2012 Nov 7;18(41):5889-96. doi: 10.3748/wjg.v18.i41.5889. PubMed PMID: 23139604; PubMed Central PMCID: PMC3491595.

[2]Gillis RA, Jolson H, Thibodeaux H, Levitt B. Antagonism of deslanoside-induced cardiotoxicity by combined nicotinic and muscarinic blockade of autonomic ganglia. J Pharmacol Exp Ther. 1975 Oct;195(1):126-32. PubMed PMID: 241837.

[3] Bakke OM, Aslaksen A, Lehmann V, Lien E. Pharmacokinetics and serum concentration--effect relationship of intravenous deslanoside. J Cardiovasc Pharmacol. 1981 Sep-Oct;3(5):1015-25. PubMed PMID: 6168847.

[4] Helke CJ, Kellar KJ, Gillis RA. Effect of in vivo deslanoside on the uptake of serotonin into platelets. Arch Int Pharmacodyn Ther. 1979 Nov;242(1):44-9. PubMed PMID: 543748.

[5] Klys M, Gross A. Determination of deslanoside in antemortem and postmortem specimens. Unusual case report. Forensic Sci Int. 1990 Apr;45(3):231-8. PubMed PMID: 2193860.

6: Tada A, Kitazawa M, Horasawa K, Zenda H, Kawa S, Oguchi T, Honma T, Furuta S. [Pharmacokinetics of deslanoside in man]. Yakugaku Zasshi. 1982 Nov;102(11):1061-6. Japanese. PubMed PMID: 7182446.7: Kobayashi M, Shimotori M, Chiba S. Direct effects of digoxin and deslanoside on sinoatrial conduction in isolated, blood-perfused dog atria. Jpn Heart J. 1983 Jul;24(4):649-55. PubMed PMID: 6645055.8: Ambrosioni E, Costa FV, Bracchetti D. Comparison of hemodynamic effects induced by pentaformilgitoxin and deslanoside in patients with heart failure. Int J Clin Pharmacol Biopharm. 1979 Oct;17(10):416-20. PubMed PMID: 500257.9: Marzo A, Ghirardi P, Maggi GC, Tornaghi A, Di Roberto F, Arisi GP. Plasma turnover and biliary and urinary excretion of deslanoside C-3H in man. Farmaco Prat. 1980 May;35(5):265-9. PubMed PMID: 7449946.10: Helke CJ, Souza JD, Gillis RA. Interaction of serotonin and deslanoside on cardiac rhythm in the cat. Eur J Pharmacol. 1978 Sep 15;51(2):167-77. PubMed PMID: 699982.1

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